Steven L. Stice Professor, Sr. Research Scientist and Eminent Scholar Animal & Dairy Science

Own this profile? Request changes

Portrait of Steven L. Stice

B.S., University of Illinois
M.S., Iowa State University
Ph.D., University of Massachusetts

Description of Research Interests

Developing animal cloning and genetic engineering technology in cattle and pigs for animal agriculture and biomedicine. My laboratory is also involved in research using embryonic stem cells as a possible treatment for neurodegenerative (Parkinson’s ALS and ALS) and vascular diseases.

Selected Recent Publications

Shin, S. Mitalipova, M., Noggle, S., Tibbitts, D., Venable, A., Rao, R.R. Stice, S.L. 2005. Long term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions. Stem Cells. published online August 11, 2005; doi:10.1634/stemcells.2004-0150.

Venable, A.M., Mitalipova, M.M., Lyons, I., Jones, K., Shin, S., Pierce, M. Stice S. 2005 Lectin binding profiles of SSEA-4 enriched, pluripotent human embryonic stem cell surfaces. BMC Developmental Biology 5 (15).

Shin, S., Dalton, S. Stice S.L. Human motor neuron differentiation from human embryonic stem cells. 2005. Stem Cells and Dev. 14(3) 266-9.

Mitalipova, M.M.; Rao, R.R.; Hoyer, D. M.; Johnson, J.A.; Meisner, L.F.; Jones,K.L.; Dalton, S., Stice, S.L. 2005. Preserving the genetic integrity of human embryonic stem cells. Nature Biotech. 23(1), 9-20.

Rao, R.R., Calhoun, J.D., Qin, X., Rekaya, R., Clark, J., and S.L. Stice. 2004. Comparative Transcriptional profiling of two human embryonic stem cell lines. Biotechnology and Bioengineering. 88(3): 273-285.

Rao, R.R., and S.L. Stice. 2004. Gene Expression Profiling of Embryonic Stem Cells Leads to Greater Understanding of Pluripotency and Early Developmental Events. Biol Reprod. 71:1772-1778.

Rao, R.R., Calhoun, J., Warrenfeltz, S., Rekaya, R., Dalton, S., McDonald, J., and S.L. Stice. 2004. Transcriptional profiling of initial differentiation events in human embryonic stem cells. Biophysical Research Communications. 323(2):453-464.

Calhoun J. D. Lambert N. , Mitilapova M. M., Noggle S., Lyons I., Condie, B., and S.L Stice. 2003. Differentiation of rhesus embryonic stem cells to neural progenitors and neurons. Biochemical and Biophysical Research Communications. 306 191-197.

Mitalipova M, Calhoun J., Shin S. Wininger D., Shulz T., Lyons I., Robins A., and S. Stice. 2003. Human embryonic stem cell lines derived from discarded embryos. Stem Cells. 21: 521-526.

McCloskey K.E., Lyons, I. Rao, R.R., Stice S. L., and R.M. Nerem. 2003. Purified and Proliferating Endothelial Cells Derived and Expanded In Vitro from Embryonic Stem Cells. Endothelium. 10:329–336.

Hodges C.A., Stice, S.L. 2003. Generation of bovine transgenics using somatic cell nuclear transfer. Reproductive Biology and Endocrinology 1:81-88.

Arat, S., Rzucidlo, S. J. and S. L. Stice. 2003. Gene expression and in vitro development of inter species nuclear transfer embryos. Molecular Reproduction and Development. 66: 334-342.

Miyoshi K., Rzucidlo S.J., Gibbons J.R., Pratt S., and S.L. Stice. 2002. Utility of rapidly matured oocytes as recipients for production of cloned embryos from somatic cells in the pig. Biol Reprod.67, 540-545.

Gibbons J, Arat S, Rzucidlo J, Miyoshi K, Waltenburg R, Respess D, Venable A, Stice S. 2002. Enhanced survivability of cloned calves derived from roscovitine-treated adult somatic cells. Biol Reprod 66:895-900.

Arat S, Gibbons J, Rzucidlo SJ, Respess DS, Tumlin M, Stice S.L. 2002. In vitro development of bovine nuclear transfer embryos from transgenic clonal lines of adult and fetal fibroblast cells of the same genotype. Biol Reprod 66:1768-74.

Miyoshi K., Rzucidlo S.J., Gibbons J.R., Arat S. and S.L. Stice. 2001. Development of porcine embryos reconstituted with somatic cells and enucleated metaphase I and II oocytes matured in a protein-free medium. BMC Developmental Biology, 1:12-17.